HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1707590Generated: October 30, 2026
4-Chlorophenyl Isocyanate → HCID 18961891, compound
https://huagongshe.com/reaction/1707590
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | 4(3H)-Quinazolinone, 3-amino-2-(ethylthio)- | HCID 11276073 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 18961891 | HCID 18961891 | — |
Reaction Steps
A mixture of 3-amino-2-ethylthio-4-quinazolone (0.60 g, 2.71 mmol) and 4-chlorophenyl isocyanate (0.48 g, 3.13 mmol) in 1,2-dichloroethane is heated at reflux for 63 hours, cooled to 0° C. and filtered. The filter cake is washed with ether and dried to give the title product as a white solid, 0.84 g (83%) mp 234°-235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05354755 |
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| Source dataset | uspto-grants-1994_10 |
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| ORD ID | ord-335ff15df13f40408bcda5a7315dd52b |
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| Source note | uspto-grants-1994_10 |
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