1-(2-Pyridyl)piperazine → HCID 15224905, compound

HRID 1707621Notes

Reaction equation

HRID 1707621 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11]([N:29]3[CH2:30][CH2:31][N:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][N:20]=4)[CH2:27][CH2:28]3)=[O:12])[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 944591-(2-Pyridyl)piperazineHCID 149759838-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride

Product 1

HCID 15224905HCID 15224905, compoundYield 81.1%

Procedure

The title compound of Example 2 (1.0 g, 3.4 mmol) was combined with 1-(2-pyridyl)piperazine (0.56 g, 3.4 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic purification, 1.16 g of the title product was obtained.

Workup

  1. custompurification

Sources & evidence

ORD record
ord-bf4e26279f4845a087b46efe0de8b390
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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