1-Ethylpiperazine → HCID 15224909, compound

HRID 1707627Notes

Reaction equation

HRID 1707627 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[CH2:20]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[CH3:21]>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11]([N:25]3[CH2:26][CH2:27][N:22]([CH2:20][CH3:21])[CH2:23][CH2:24]3)=[O:12])[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 791961-EthylpiperazineHCID 149759838-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride

Product 1

HCID 15224909HCID 15224909, compoundYield 87%

Procedure

The title compound of Example 2 (1.0 g, 3.4 mmol) was combined with 4-ethylpiperazine (0.43 g, 3.7 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic purification, 1.10 g of the title product was obtained as a pale yellow solid.

Workup

  1. custompurification

Sources & evidence

ORD record
ord-57e0eb76c50a4f81b6b77bf4723acded
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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