HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 15046665, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 15046659 | HCID 15046659 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15046665 | HCID 15046665 | — |
Reaction Steps
The title compound is prepared by the procedure of Example 52 using 19.6 g of (R)-3-hydroxy-1-(2-propynyl)-2-pyrrolidinone, 26.6 ml of acetic anhydride, 17 ml of pyridine, 0.6 g of 4-(dimethylamino)pyridine and 200 ml of methylene chloride to give 23.4 g of the desired product as a pale yellow oil. [α]D26° =+59° (methylene chloride).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05356885 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-ec4401534edf423da94406a1748e59a8 |
| Source note | uspto-grants-1994_10 |