HCID 15100222, compound → HCID 15100223, compound

Participants

Reaction Steps

A solution of 3.1 g (17 mmol) of 1-methyl-4-chloro-5-imidazolesulfonic acid from Example 5 in 100 ml of water is hydrogenated to constant pressure at 25° C. in the presence of 0.5 g of Pd/C catalyst with shaking at an initial pressure of 3.45 bar of hydrogen. The crystalline residue remaining after filtering off the catalyst and evaporating the water in vacuo is recrystallized from ethanol in order to give the title compound of melting point 286°-287° C.

Provenance & Evidence