Hydrochloric Acid → HCID 18961239, compound

Participants

Reaction Steps

A mixture consisting of 1,3-diphthalimido-2-ethylpropane (25 g, 69 mmol) concentrated hydrochloric acid (700 mL), and ethanol (700 mL) was refluxed for 6 days with additional concentrated hydrochloric acid being added at the indicated time; 3 days (300 mL), 4 days (200 mL), 5 days (200 mL). The reaction was evaporated to dryness and the residue was diluted with water (200 mL), chilled, and filtered. The filtrate was washed with ethyl acetate (5×500 mL) and evaporated to leave 12 g (100%) of 2-ethyl-1,3-propanediamine dihydrochloride as a thick oil.

Provenance & Evidence