HCID 10474143, compound → HCID 18958849, compound

Participants

Reaction Steps

10 g of 7-n-propyl-5-methyl-8-[(2'-cyano-4-biphenylyl)methyl]-1,2,4-triazolo[4,3-c]pyrimidine, prepared in Example 69, are heated to reflux for 4 hours in 150 ml of formic acid. The mixture is evaporated to dryness under vacuum, and the residue, taken up with ether and pentane, crystallises to give 7.5 g of 7-n-propyl-5-methyl-8-[(2'-cyano-4-biphenylyl)methyl]-1,2,4-triazolo[1,5-c]pyrimidine in the form of crystals of melting point 112° C.

Provenance & Evidence