HCID 18958851, compound → HCID 18958839, compound

Participants

Reaction Steps

A solution of 15.5 g of 7-n-propyl-5-methyl-1,2,4-triazolo[4,3-c]pyrimidin-3(2H)-one, prepared in Example 192, in 100 ml of acetic acid is heated to reflux for 20 h. The reaction mixture is then evaporated under vacuum, and the residue obtained crystallises in ethyl ether. The drained crystals are washed with ethyl ether and dried. 12 g of 7-n-propyl-5-methyl-1,2,4-triazolo[1,5-c]pyrimidin-2(3H)-one are obtained in the form of crystals of melting point 173° C.

Provenance & Evidence