Ethyl 2-aminobenzoate → HCID 18958955, compound

HRID 1708564Notes

Reaction equation

HRID 1708564 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[Cl:13][C:14]1[CH:19]=[CH:18][N:17]=[CH:16][C:15]=1[N+:20]([O-:22])=[O:21]>C(O)C>[ClH:13].[N+:20]([C:15]1[CH:16]=[N:17][CH:18]=[CH:19][C:14]=1[NH:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5])([O-:22])=[O:21]

Participants

4

Reactant 2

HCID 6877Ethyl 2-aminobenzoateHCID 27357814-Chloro-3-nitropyridine

Product 1

HCID 18958955HCID 18958955, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of ethyl 2-aminobenzoate (3.17 g, 20 mmol) and 4-chloro-3-nitropyridine (2.8 ml) in ethanol (150 ml) was stirred at room temperature for 60 hours. The resulting precipitate was collected, washed with ethanol and dried to give ethyl 2-(3-nitro-4-pyridylamino)benzoate hydrochloride (3.9 g) as a yellow crystalline solid, m.p. 192°-205° C.

Workup

  1. customThe resulting precipitate was collected
  2. washwashed with ethanol
  3. customdried

Sources & evidence

ORD record
ord-6c029175a1954ecc859a7137ad950db5
Source dataset
uspto-grants-1994_10
Patent number
US05358953

Reaction notes

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