HuagongsheHuagongshe Chemistry Print Report · For research reference only
21,21-Dimethoxy-20-methylpregn-6-ene-1alpha,3beta,5a-triol → 20-(1,3-Dioxolan-2-yl)-3beta-acetoxy-1alpha-benzoyloxypregn-6-en-5alpha-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 21,21-Dimethoxy-20-methylpregn-6-ene-1alpha,3beta,5a-triol | HCID 57085412 | — |
| Reactant | 20-(1,3-Dioxolan-2-yl)-3beta-acetoxypregn-6-ene-1alpha,5alpha-diol | HCID 67852965 | — |
| Product | 20-(1,3-Dioxolan-2-yl)-3beta-acetoxy-1alpha-benzoyloxypregn-6-en-5alpha-ol | HCID 67852961 | 92.8% |
Reaction Steps
The reaction and workup procedures of Example 105 were repeated except that 350 mg of 20-(1,3-dioxolan-2-yl)-3β-acetoxypregn-6-ene-1α,5α-diol was used in lieu of 400 mg of 21,21-dimethoxy-20-methylpregn-6-ene-1α,3β,5α-triol to give 400 mg of 20-(1,3-dioxolan-2-yl)-3β-acetoxy-1α-benzoyloxypregn-6-en-5α-ol showing the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359055 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-99bebc4f970d4b75985bf65e3295ae74 |
| Source note | uspto-grants-1994_10 |