Pyrazole → HCID 178522630, compound

Participants

Reaction Steps

Next, 304 g (0.6 mol) of the 1-(2,4,6-trichlorophenyl)-3-(3-nitrobenzamido)-4-bromo-5-oxo-2pyrazoline and 163 g (2.4 mol) of pyrazole were mixed well and then heated to react for about 5 to 6 hours at 80° to 90° C in a stream of nitrogen gas. The mixture was then cooled to room temperature, 700 ml of acetonitrile was added, and the deposited crystals were thereafter filtered to obtain 197 g (66 %) of 1-(2,4,6-trichlorophenyl)-3-(3-nitrobenzamido)-4-pyrazolyl-5-oxo-2-pyrazoline.

Provenance & Evidence