Acetamidomalonic acid diethyl ester → HCID 14851180, compound

HRID 1709021Notes

Reaction equation

HRID 1709021 reaction equation
[C:1]([NH:4][CH:5]([C:9]([OH:11])=[O:10])[C:6]([OH:8])=[O:7])(=[O:3])[CH3:2].[Ba:12].[OH-].[Ba+2].[OH-].C(OC(=O)C(NC(=O)C)C(OCC)=O)C>O>[C:1]([NH:4][CH:5]([C:9]([O-:11])=[O:10])[C:6]([O-:8])=[O:7])(=[O:3])[CH3:2].[Ba+2:12]

Participants

5

Reactant 3

HCID 14041Acetamidomalonic acid diethyl esterHCID 6093286Barium hydroxideHCID 86744137HCID 86744137, compound

Product 1

HCID 14851180HCID 14851180, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Preparation of Barium acetamidomalonic acid--To 14.5 g (46.0 mmol) of barium hydroxide in 750 ml of water is added 10.0 g (46 mmol) of acetamidomalonic acid diethyl ester. The solution is refluxed for one hour and suction filtered while still hot. The filtrate is allowed to cool to room temperature to give barium acetamidomalonate in quantitative yield as white crystals. IR (KBr) 3366.8, 1654, 1640, 1599, 1578,1530, 1427, 1344 cm-1. Elemental analysis for BaC5H

Workup

  1. temperatureThe solution is refluxed for one hour
  2. filtrationsuction filtered while still hot

Sources & evidence

ORD record
ord-349c5391daf540e097c28a482621d69d
Source dataset
uspto-grants-1990_08
Patent number
US04946954

Reaction notes

Loading…