Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Succinimide | HCID 11439 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Hydride | HCID 166653 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Boron | HCID 5462311 | — |
| Product | HCID 15696556 | HCID 15696556 | — |
Reaction Steps
28.4 g of succinimide in 1200 cm3 of isopropanol is cooled to -10° C., 32.8 g of hydride of boron and sodium is added, and after agitating for 4 hours at 0°/-10° C., there is added a 2N solution of hydrochloric acid in isopropanol, adjusting the pH to 2-3. This is maintained for 2 hours at 0° C., then neutralised with a solution of potassium hydroxide in isopropanol. The solvent is evaporated under reduced pressure, the residue is taken up with chloroform, concentrated to dryness under reduced pressure, and 20.5 g of the expected product is obtained. m.p. 68°-71° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04948804 |
|---|
| Source dataset | uspto-grants-1990_08 |
|---|
| ORD ID | ord-bc0f91fe2d9d4ed391ebe67dbf497a40 |
|---|
| Source note | uspto-grants-1990_08 |
|---|
