HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pentanol → 5-Pentyloxy-pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pentanol | HCID 6276 | — |
| Reactant | 5-Hydroxy-2-pyrrolidone | HCID 194148 | — |
| Product | 5-Pentyloxy-pyrrolidin-2-one | HCID 15696558 | — |
Reaction Steps
A mixture of 2.5 g of 5-hydroxy-pyrrolidin-2-one and 1.25 g of Amberlite IR 120 H is agitated at 65° C. for 3 hours in 55 cm3 of n-pentanol. After cooling to ambient temperature, filtering, and distilling under reduced pressure, the residue is chromatographed on silica (eluent: ethyl acetate), and 2.68 g of the expected product is obtained. m.p. 42°-43° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04948804 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-f64b0df4872c4548867a74698a0cd1e0 |
| Source note | uspto-grants-1990_08 |