Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Hexanol | HCID 8103 | — |
| Reactant | 5-Hydroxy-2-pyrrolidone | HCID 194148 | — |
| Product | 5-(n-Hexyloxy)-pyrrolidin-2-one | HCID 15696563 | — |
Reaction Steps
A mixture of 0.4 g of 5-hydroxy-pyrrolidin-2-one, 10 cm3 of n-hexanol and 0.2 g of Amberlite IR 120 H is agitated at 60° C. for 3 hours. After cooling, the solvent is distilled off and the residue is chromatographed on silica, (eluent: ethyl acetate); 0.5 g of the product sought is obtained. m.p. 35°-37° C., crystallized from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04948804 |
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| Source dataset | uspto-grants-1990_08 |
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| ORD ID | ord-3f42e65dfe3a4a90a7d157d334687f33 |
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| Source note | uspto-grants-1990_08 |
|---|
