反应详情

温度

60 °C

A mixture of 0.4 g of 5-hydroxy-pyrrolidin-2-one, 10 cm3 of n-hexanol and 0.2 g of Amberlite IR 120 H is agitated at 60° C. for 3 hours. After cooling, the solvent is distilled off and the residue is chromatographed on silica, (eluent: ethyl acetate); 0.5 g of the product sought is obtained. m.p. 35°-37° C., crystallized from hexane.

1. temperatureAfter cooling
2. distillationthe solvent is distilled off
3. customthe residue is chromatographed on silica, (eluent: ethyl acetate)