1-Octanol → HCID 15696565, compound

HRID 1709190Notes

Reaction equation

HRID 1709190 reaction equation
[OH:1][CH:2]1[NH:6][C:5](=[O:7])[CH2:4][CH2:3]1.[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>>[CH2:8]([O:1][CH:2]1[NH:6][C:5](=[O:7])[CH2:4][CH2:3]1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 9571-OctanolHCID 1941485-Hydroxy-2-pyrrolidone

Product 1

HCID 15696565HCID 15696565, compound

Conditions

Temperature
60 °C

Procedure

A mixture of 7.5 g of 5-hydroxy-pyrrolidin-2-one in 10 cm3 of n-octanol and 4 g of Amberlite IR 120 H is agitated at 60° C. for 4 hours. After filtering, and concentrating to dryness, 5.5 g of the expected product is obtained, m.p. 36°-38° C., crystallized from hexane. By re-crystallizing from hexane, m.p.=38°-40° C.

Workup

  1. filtrationAfter filtering
  2. concentrationconcentrating to dryness

Sources & evidence

ORD record
ord-cd41fec10f004abf989df23e0eab2e47
Source dataset
uspto-grants-1990_08
Patent number
US04948804

Reaction notes

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