反应详情

5.5 g of 5-hydroxy-pyrrolidin-2-one, 30 cm3 of 2-pentanol and 2.75 g of Amberlite-15 resin are agitated for 5 hours at ambient temperature. After filtering, the excess pentanol is distilled off under 1 mm Hg at 40° C. The residue is chromatograp:hed on silica, (eluent: ethyl acetate), and 3.7 g of the expected product is obtained.

1. filtrationAfter filtering
2. distillationthe excess pentanol is distilled off under 1 mm Hg at 40° C