Bromine → HCID 14878026, compound

HRID 1709250Notes

Reaction equation

HRID 1709250 reaction equation
[C:1]([C:4]1[CH:5]=[C:6](/[CH:10]=[CH:11]/[C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].[Br:17]Br>C(O)C.O1CCOCC1>[Br:17][CH2:2][C:1]([C:4]1[CH:5]=[C:6](/[CH:10]=[CH:11]/[C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:7]=[CH:8][CH:9]=1)=[O:3]

Participants

5

Reactant 2

HCID 24408BromineHCID 14835687HCID 14835687, compound

Product 1

HCID 14878026HCID 14878026, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 312751,4-DioxaneSolvent

Procedure

10.9 g of ethyl (E)-3-(3-acetylphenyl)acrylate was dissolved in 50 ml of ethanol and 5 ml of dioxane. To the solution was dropwise added 8.8 g of bromine in 2 hours at 15° to 20° C. The mixture was stirred for 1 hour at the same temperature. The solvent was removed by distillation under reduced pressure to obtain ethyl (E)-3-[3-(2-bromoacetyl)phenyl]acrylate.

Workup

  1. customin 2 hours
  2. customat 15° to 20° C
  3. customThe solvent was removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-09a92b4e87f24e9ba1561793d208ec81
Source dataset
uspto-grants-1990_08
Patent number
US04948796

Reaction notes

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