HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hypochlorite → HCID 178506304, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hypochlorite | HCID 23665760 | — |
| Reactant | 5-chloro-3-(trifluoromethyl)-1H-pyrazole | HCID 178506197 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178506304 | HCID 178506304 | — |
Reaction Steps
A solution of 5-chloro-3-trifluoromethylpyrazole (190.0 g, 1.11 mol) in 400 ml of methanol is treated with liquid bleach (5.25% NaOCl) for 3 hr. The reaction mixture is then extracted with ether, the combined ether extracts are acidified with HCl (300 ml), washed with brine, dried and concentrated to give 4,5-dichloro-3-trifluoromethylpyrazole, a light yellow solid, m.p. 58°-60° .
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04950678 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-955e6731d4834cf980e08587bfdc5f65 |
| Source note | uspto-grants-1990_08 |