HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 14407071, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2H-1-Benzopyran-2-one, 7-(3-chloropropoxy)- | HCID 1900666 | — |
| Reactant | Bis(4-fluorophenyl)(piperidin-4-yl)methanol | HCID 11208889 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 14407071 | HCID 14407071 | 71.2% |
Reaction Steps
This compound was prepared according to the procedure of Example 1. A mixture of 3.0 g (0.01 mole) of α,α-bis(p-fluorophenyl)-4-piperidinemethanol, 2.4 g (0.01 mole of 7-(3-chloropropoxy)2H-1-benzopyran-2-one, 5.3 g (0.05 mole) of anhydrous sodium carbonate and 0.3 g of potassium iodide in 100 ml of 1-butanol gave 3.6 g (71%) of pale yellow crystals, m.p. 99°-120° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04950674 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-4c783a4d413d42b989375c749119b846 |
| Source note | uspto-grants-1990_08 |