HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 15093867, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-(3-Chloropropoxy)-3-methoxyacetophenone | HCID 7314264 | — |
| Reactant | HCID 19992282 | HCID 19992282 | — |
| Reactant | 4-(Diphenylmethylene)-1-(3-phenoxypropyl)piperidine oxalate | HCID 23036335 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 15093867 | HCID 15093867 | 50.4% |
Reaction Steps
This compound was prepared according to the procedure used to synthesize the compound of Example 1. A mixture of 1.4 g (0.004 mole) of α,α-bis(3,4-difluorophenyl)-4-piperidinemethanol, 1.0 g (0.004 mole) of 1-[4-(3-chloropropoxy)-3-methoxyphenyl]ethanone, 1.6 g (0.015 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave 1.1 g (48%) of the title compound as an off-white solid, mp 143°-146° C. (2-propanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04950674 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-4257a6e9ded945cb8a4a60831387cc49 |
| Source note | uspto-grants-1990_08 |