反应详情

59 g of hydrazine hydrate was dissolved in 712 ml of acetonitrile at room temperature under an atmosphere of nitrogen. A solution obtained by dissolving 46.3 g of 1,2-dichloro-4-nitrobenzene in 71 g of acetonitrile was added dropwisely to the obtained solution. After the addition had been completed, the obtained mixture was subjected to reflux by heat for 4 hours, and the reaction solution was concentrated. 500 g of water was added to the concentrate, and the produced crystals were filtered off. 200 g of acetonitrile was then added to the crystals, and the obtained mixture was subjected to reflux by heat for 30 minutes and then cooled with ice to room temperature. The produced crystals were filtered off (yield: 27 g).

1. customA solution obtained
2. additionwas added dropwisely to the obtained solution
3. additionAfter the addition
4. temperatureto reflux
5. temperatureby heat for 4 hours
6. concentrationthe reaction solution was concentrated
7. addition500 g of water was added to the concentrate
8. filtrationthe produced crystals were filtered off
9. addition200 g of acetonitrile was then added to the crystals
10. temperatureto reflux
11. temperatureby heat for 30 minutes
12. filtrationThe produced crystals were filtered off (yield: 27 g)