Potassium Hydroxide → HCID 23035827, compound

HRID 1710203Notes

Reaction equation

HRID 1710203 reaction equation
[CH2:1]([C:10]1[S:11][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23]C)=[O:22])=[CH:17][CH:16]=2)=[N:13][N:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[OH-].[K+]>CO>[CH2:1]([C:10]1[S:11][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([OH:23])=[O:22])=[CH:17][CH:16]=2)=[N:13][N:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 23035824HCID 23035824, compound

Product 1

HCID 23035827HCID 23035827, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-Nonyl-5-(4-methoxycarbonylphenyl)-1,3,4-thiadiazole (0.02 moles, 7.4 g) is added to a solution of 0.2 moles (11.2 g) KOH in 400 mL methanol and heated for 2 hours at the boiling point. The solvent is distilled of in a rotary evaporator and the residue is dissolved in 200 mL of water and acidified with concentrated hydrochloric acid.

Workup

  1. temperatureheated for 2 hours at the boiling point
  2. distillationThe solvent is distilled of in a rotary evaporator
  3. dissolutionthe residue is dissolved in 200 mL of water

Sources & evidence

ORD record
ord-6d47f351fff24187a4e2d9a02d16398f
Source dataset
uspto-grants-1990_08
Patent number
US04952699

Reaction notes

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