Carbon Disulfide → HCID 23682911, compound

HRID 1710247Notes

Reaction equation

HRID 1710247 reaction equation
[C:1]([NH:4][CH2:5][CH2:6][SH:7])(=[O:3])[CH3:2].[OH-].[K+:9].[C:10](=[S:12])=[S:11]>C(O)C>[C:1]([NH:4][CH2:5][CH2:6][S:7][C:10](=[S:11])[S-:12])(=[O:3])[CH3:2].[K+:9]

Participants

5

Reactant 3

HCID 6348Carbon DisulfideHCID 14484AcetylcysteamineHCID 14797Potassium Hydroxide

Product 1

HCID 23682911HCID 23682911, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent3×

Procedure

A solution of 1.708 g (14.35 mmole) of 2-acetylaminoethyl mercaptan in 2 ml of absolute ethanol is added dropwise over the course of 0.5 hours, while stirring and cooling to 10°-15°, to a solution of 0.80 g (14.35 mmole) of potassium hydroxide in 5 ml of absolute ethanol. After a further half hour, a solution of 1.09 g (14.35 mmole) of carbon disulphide in 3 ml of absolute ethanol is added, the temperature being maintained at 10°-15°. The reaction mixture is further stirred for 3 hours at room temperature and cooled in an ice bath for 20 minutes. The yellow crystalline precipitate is filtered off, washed once with absolute ethanol and yields potassium (2-acetylaminoethyl)-trithiocarbonate having a melting point of 171°-174°.

Workup

  1. temperaturethe temperature being maintained at 10°-15°
  2. stirringThe reaction mixture is further stirred for 3 hours at room temperature
  3. temperaturecooled in an ice bath for 20 minutes
  4. filtrationThe yellow crystalline precipitate is filtered off
  5. washwashed once with absolute ethanol

Sources & evidence

ORD record
ord-80a93579e705407098ef420853e28d63
Source dataset
uspto-grants-1990_08
Patent number
US04952690

Reaction notes

Loading…