1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-Isoquinolin-5-yl-3-(4-trifluoromethoxy-benzyl)-urea
Reaction equation
[CH2:14]1[CH2:15][CH2:16][C:17]2=[N:22][CH2:21][CH2:20][CH2:19][N:18]2[CH2:23][CH2:24]1.[Cl:25][C:26]([C:27](=[O:28])[NH:29][c:30]1[c:31]2[cH:32][cH:33][n:34][cH:35][c:36]2[cH:37][cH:38][cH:39]1)([Cl:40])[Cl:41].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][NH2:9])[cH:10][cH:11]1)([F:12])[F:13]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][NH:9][C:27](=[O:28])[NH:29][c:30]2[c:31]3[cH:32][cH:33][n:34][cH:35][c:36]3[cH:37][cH:38][cH:39]2)[cH:10][cH:11]1)([F:12])[F:13]Participants
4
Sources & evidence
- ORD record
- ord-1cfc8645f75f4e098c970e38736b8da4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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