Piperidin-4-ol → HCID 25203982, compound

HRID 1710356Notes

Reaction equation

HRID 1710356 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1Cl)=[O:13])[CH2:8]2.[OH:26][CH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1[N:30]1[CH2:31][CH2:32][CH:27]([OH:26])[CH2:28][CH2:29]1)=[O:13])[CH2:8]2

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 575502625-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide2×

Product 1

HCID 25203982HCID 25203982, compound

Procedure

5-(4-Hydroxy-piperidin-1-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 4-hydroxypiperidine. Mass spectrum (ES) MH+=421.

Sources & evidence

ORD record
ord-feba16a336274786b590c0c404dfce46
Source dataset
uspto-grants-2010_09
Patent number
US07790711B2

Reaction notes

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