1-Amino-2-propanol → HCID 25204053, compound

HRID 1710359Notes

Reaction equation

HRID 1710359 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1Cl)=[O:13])[CH2:8]2.[NH2:26][CH2:27][CH:28]([OH:30])[CH3:29]>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1[NH:26][CH2:27][CH:28]([OH:30])[CH3:29])=[O:13])[CH2:8]2

Participants

3

Reactant 2

HCID 41-Amino-2-propanolHCID 575502625-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide2×

Product 1

HCID 25204053HCID 25204053, compound

Procedure

5-(2-Hydroxy-propylamino)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 1-amino-2-propanol. Mass spectrum (ES) MH+=395.

Sources & evidence

ORD record
ord-bdc5a1c25223425aa50877fd45544186
Source dataset
uspto-grants-2010_09
Patent number
US07790711B2

Reaction notes

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