HRID1710511

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

HCID143368

Indole-3-carboxylic acid, 1-methyl-, ethyl ester

C12H13NO2

HCID10775338

Ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate

C12H12FNO2

PRODUCTS

生成物

HCID22593743

5-Fluoro-N,1-dimethyl-1H-indole-2-carboxamide

C11H11FN2O

收率 68%

PROCEDURE

实验过程

According to the procedure of Preparation 1 (b), except substituting ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate for the ethyl 1-methyl-1H-indole-2-carboxy late, the title compound (2.1 g, 68%) was prepared as a white solid: MS (ES) m/e 207 (M+H)+.