HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl((1-methyl-1H-indol-2-yl)methyl)amine → [(5-Fluoro-1H-indol-2-yl)methyl]-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl((1-methyl-1H-indol-2-yl)methyl)amine | HCID 11401058 | — |
| Reactant | N,1-dimethylindole-2-carboxamide | HCID 12303315 | — |
| Reactant | N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide | HCID 22593743 | — |
| Product | [(5-Fluoro-1H-indol-2-yl)methyl]-methylamine | HCID 22593726 | 78% |
Reaction Steps
According to the procedure of Preparation 1 (c), except substituting N,1-dimethyl-5-fluoro-1H-indole-2-carboxamide for the N,1-dimethyl-1H-indole-2-carboxamide, the title compound (1.5 g, 78%) was prepared as a white solid: MS (ES) m/e 193 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790716B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-e4f2f78bf0724edbad000d92af5a3517 |
| Source note | uspto-grants-2010_09 |