Hydrochloric Acid → HCID 67095157, compound

HRID 1710605Notes

Reaction equation

HRID 1710605 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[C:18]([N:20]([S:22]([C:25]3[C:33]4[O:32][C:31]([F:35])([F:34])[O:30][C:29]=4[CH:28]=[CH:27][CH:26]=3)(=[O:24])=[O:23])C)[CH:17]=[CH:16][C:15]=2[O:36][CH3:37])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:38]>CCOCC.ClCCl>[ClH:38].[CH3:37][O:36][C:15]1[CH:16]=[CH:17][C:18]([NH:20][S:22]([C:25]2[C:33]3[O:32][C:31]([F:35])([F:34])[O:30][C:29]=3[CH:28]=[CH:27][CH:26]=2)(=[O:24])=[O:23])=[CH:19][C:14]=1[N:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67094964HCID 67094964, compound

Product 1

HCID 67095157HCID 67095157, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared by treatment of 4-{5-[(2,2-Difluoro-benzo[1,3]dioxole-4-sulfonyl)-methyl-amino]-2-methoxy-phenyl}-piperazine-1-carboxylic acid tert-butyl ester with HCl in ether and dichloromethane as solvent.

Sources & evidence

ORD record
ord-f59bdeba70474e998ec6b5db3682ab91
Source dataset
uspto-grants-2010_09
Patent number
US07790727B2

Reaction notes

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