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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1710624Generated: November 4, 2026

2,2-Difluoro-2H-1,3-benzodioxole-4-sulfonyl chloride → HCID 67094937, compound

https://huagongshe.com/reaction/1710624

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluoro-2H-1,3-benzodioxole-4-sulfonyl chlorideHCID 17750111—
Reactanttert-Butyl 4-(3-aminophenyl)piperazine-1-carboxylateHCID 22330182—
ProductHCID 67094937HCID 67094937—

Reaction Steps

The compound was prepared as described for Example 28 by reaction of 4-(5-aminophenyl)-piperazine-1-carboxylic acid tert-butyl ester with commercially available 2,2-Difluorobenzo[1,3]dioxole-4-sulfonyl chloride followed by deprotection under acidic conditions.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790727B2
Source datasetuspto-grants-2010_09
ORD IDord-e322331f344041188dd780fd545d3220
Source noteuspto-grants-2010_09