HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Fluorophenyl)methyl]piperidin-4-ol → 2-Chloro-1-[4-(4-fluoro-benzyl)-4-hydroxy-piperidin-1-yl]-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Fluorophenyl)methyl]piperidin-4-ol | HCID 10488624 | — |
| Reactant | 1-(2-Chloro-acetyl)-3-(3-chloro-2-methyl-phenyl)-imidazolidin-4-one | HCID 59434027 | — |
| Product | 2-Chloro-1-[4-(4-fluoro-benzyl)-4-hydroxy-piperidin-1-yl]-ethanone | HCID 58834340 | — |
Reaction Steps
2-Chloro-1-[4-(4-fluoro-benzyl)-4-hydroxy-piperidin-1-yl]-ethanone was prepared from 4-(4-fluorobenzyl)piperidin-4-ol according to the procedure described for Compound 76 in Example 40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790726B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-e1950f22ab1d4c3e9f84acee99be3893 |
| Source note | uspto-grants-2010_09 |