HCID 16070453, compound → HCID 16070222, compound

Participants

Reaction Steps

To a solution of 3-ethynyl-6-(2-furyl)-5-pyridin-4-ylpyrazin-2-amine (Example 65, 50 mg, 0.19 mmol) in ethanol (4 mL) was added platinum dioxide (5 mg). The mixture was hydrogenated at 1 atmosphere and at room temperature for 18 h, filtered, washed with methanol and dichloromethane and evaporated to give the title compound as a white solid (44 mg, 88%).

Provenance & Evidence