HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59457562, compound → HCID 178522379, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59457562 | HCID 59457562 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178522379 | HCID 178522379 | 27.1% |
Reaction Steps
To a stirred solution of N-[6-(6-benzyloxypyridin-3-yl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide (0.22 g, 0.51 mmol) in ethanol (11 mL) was added palladium on activated carbon (10%) (0.033 g) and the mixture was hydrogenated under atmospheric pressure. After 18 h, the mixture was filtered, washed with ethanol and evaporated under vacuum to provide the titled compound as a brown solid (0.046 g, 27%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790728B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-fafbd0ee16b545c18e21001cab6e0314 |
| Source note | uspto-grants-2010_09 |