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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1710722Generated: November 3, 2026

HCID 59457562, compound → HCID 178522379, compound

https://huagongshe.com/reaction/1710722

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59457562HCID 59457562—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178522379HCID 17852237927.1%

Reaction Steps

To a stirred solution of N-[6-(6-benzyloxypyridin-3-yl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide (0.22 g, 0.51 mmol) in ethanol (11 mL) was added palladium on activated carbon (10%) (0.033 g) and the mixture was hydrogenated under atmospheric pressure. After 18 h, the mixture was filtered, washed with ethanol and evaporated under vacuum to provide the titled compound as a brown solid (0.046 g, 27%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790728B2
Source datasetuspto-grants-2010_09
ORD IDord-fafbd0ee16b545c18e21001cab6e0314
Source noteuspto-grants-2010_09