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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1711141Generated: November 2, 2026

3-Methylbenzylamine → HCID 22643530, compound

https://huagongshe.com/reaction/1711141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylbenzylamineHCID 66015—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ProductHCID 22643530HCID 2264353082%

Reaction Steps

Using general procedure A, 3-methylbenzylamine (198 μL, 1.58 mmol) and 1-Boc-4-piperidone (300 mg, 1.51 mmol) afforded 4-(3-methylbenzylamino)-piperidine-1-carboxylic acid tert-butyl ester as a white solid (375 mg, 82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790747B2
Source datasetuspto-grants-2010_09
ORD IDord-41e1704cf51141598d138171fd9677f3
Source noteuspto-grants-2010_09