Ethylamine → HCID 178503883, compound

HRID 1711175Notes

Reaction equation

[CH2:1]([NH:3][C:4](=[N:7][C:8]#[N:9])[S:5][CH3:6])[CH3:2].[CH:10]1(N)CC[CH2:11]1.C(N)C>>[CH:1]1([NH:3][C:4](=[N:7][C:8]#[N:9])[S:5][CH3:6])[CH2:11][CH2:10][CH2:2]1

Participants

Reactant 3

HCID 6341Ethylamine

HCID 75645Cyclobutylamine

HCID 178464595HCID 178464595, compound

Product 1

HCID 178503883HCID 178503883, compound

Procedure

1-Cyclobutyl-2-methyl-3-cyanoisothiourea was prepared following the same procedure as for 1-ethyl-2-methyl-3-cyanoisothiourea (see EXAMPLE 250) except that cyclobutylamine was used in lieu of ethylamine. 1H NMR (CDCl3) δ 1.62-1.79 (m, 2H), 1.92-2.08 (m, 2H), 2.29-2.45 (m, 5H), 4.11 (br s, 1H), 6.74 (br s, 1H).

Sources & evidence

ORD record: ord-22d8d8b5b9674b3ab9b5f46a9f3e61fe
Source dataset: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07790747B2

Reaction notes

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