反应详情

1-Cyclobutyl-2-methyl-3-cyanoisothiourea was prepared following the same procedure as for 1-ethyl-2-methyl-3-cyanoisothiourea (see EXAMPLE 250) except that cyclobutylamine was used in lieu of ethylamine. 1H NMR (CDCl3) δ 1.62-1.79 (m, 2H), 1.92-2.08 (m, 2H), 2.29-2.45 (m, 5H), 4.11 (br s, 1H), 6.74 (br s, 1H).