HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 68774675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 68773942 | HCID 68773942 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68774675 | HCID 68774675 | 77.8% |
Reaction Steps
[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-ethyl]-carbamic acid tert-butyl ester (1.1 g, 1.92 mmol) was treated with hydrazine hydrate (0.5 ml, 9 mmol) in EtOH (5 ml) at rt over night to give [(S)-1-aminomethyl-2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-carbamic acid tert-butyl ester (640 mg, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790747B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-3c7afa4a5832430c8f6e35f64ac8022d |
| Source note | uspto-grants-2010_09 |