Hydrazine → HCID 68503406, compound

HRID 1711330Notes

Reaction equation

HRID 1711330 reaction equation
CS[C:3]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)=[CH:4][N+:5]([O-:7])=[O:6].[NH2:14][NH2:15]>CCO>[N+:5]([CH:4]=[C:3]([NH:14][NH2:15])[N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)([O-:7])=[O:6]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 53823551HCID 53823551, compound

Product 1

HCID 68503406HCID 68503406, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-(1-Methylsulfanyl-2-nitro-vinyl)-piperidine (WO 2000016766, 202 mg, 1.00 mmol) was reacted with hydrazine (30 μL, 1.0 mmol) in EtOH to afford (2-nitro-1-piperidin-1-yl-vinyl)-hydrazine and which was converted to 4-nitro-3-piperidin-1-yl-pyridazine following procedures analogous to literature methods (Tett. Lett. 41, 3619, (1977)).

Sources & evidence

ORD record
ord-3e890b06ac1542638941cf947051612a
Source dataset
uspto-grants-2010_09
Patent number
US07790724B2

Reaction notes

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