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HRID1711753

反应详情

EQUATION

反应方程式

HRID 1711753 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccc(O)cc1C(F)(F)F
HCID6931

3-(Trifluoromethyl)-4-nitrophenol

C7H4F3NO3

结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(O)C1
HCID58673070

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(Oc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C1
HCID58673080

未命名化合物

收率 56%

PROCEDURE

实验过程

Prepared in analogy to Example 4 from rac-(3-hydroxy-pyrrolidin-1-yl)-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone (Example 9(a)) and 5-hydroxy-2-nitrobenzotrifluoride. The crude material was purified by reversed phase HPLC (acetonitrile/water) to yield the title compound as an amorphous white solid (yield 56%). MS (m/e): 517.5 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by reversed phase HPLC (acetonitrile/water)