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HRID1711759

反应详情

EQUATION

反应方程式

HRID 1711759 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1cccc(OC2CNC2)c1
HCID11138538

3-[3-(trifluoromethyl)phenoxy]azetidine

C10H10F3NO

结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100237

2-(1-Methylethoxy)-5-(methylsulfonyl)benzoic acid

C11H14O5S

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CC(Oc2cccc(C(F)(F)F)c2)C1
HCID11712232

未命名化合物

收率 7%

PROCEDURE

实验过程

Prepared in analogy to Example 1 from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example A1) and 3-(3-trifluoromethyl-phenoxy)-azetidine. The crude material was purified by chromatography (methanol/dichloromethane) to yield the title compound as an amorphous white solid (yield 7%). MS (m/e): 458.2 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (methanol/dichloromethane)