Pyridine → HCID 58903234, compound

HRID 1711807Notes

Reaction equation

HRID 1711807 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:13]=[C:14]([NH2:16])[CH:15]=1)[C:5]([NH:7][CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1)=[O:6].[CH:17]1([C:22](Cl)=[O:23])[CH2:21][CH2:20][CH2:19][CH2:18]1.CN1[C:30](=[O:31])[CH2:29][CH2:28][CH2:27]1.[Li+].[Cl-].N1C=CC=[CH:36][CH:35]=1>>[CH:8]1([NH:7][C:5](=[O:6])[C:4]2[CH:13]=[C:14]([NH:16][C:22]([CH:17]3[CH2:21][CH2:20][CH2:19][CH2:18]3)=[O:23])[CH:15]=[C:2]([NH:1][C:30]([CH:29]3[CH2:36][CH2:35][CH2:27][CH2:28]3)=[O:31])[CH:3]=2)[CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

6

Reactant 5

HCID 1049PyridineHCID 13387N-methyl-2-pyrrolidoneHCID 78284Cyclopentanecarbonyl chlorideHCID 433294Lithium ChlorideHCID 61090893HCID 61090893, compound

Product 1

HCID 58903234HCID 58903234, compound

Procedure

from 0.50 g (228 mmol) of 3,5-diamino-N-cyclopentyl-benzamide, 0.71 g (5.35 mmol) of cyclopentanecarbonylchloride, 30 ml of NMP, 5 ml of pyridine and 0.05 g of LiCl according to Method A.

Sources & evidence

ORD record
ord-ffc462c240cd4d069c03d64c1658fef8
Source dataset
uspto-grants-2010_09
Patent number
US07790793B2

Reaction notes

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