Pyridine → HCID 58903272, compound

HRID 1711808Notes

Reaction equation

HRID 1711808 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:13]=[C:14]([NH2:16])[CH:15]=1)[C:5]([NH:7][CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1)=[O:6].[CH:17]1([C:23](Cl)=[O:24])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1.CN1[C:31](=[O:32])[CH2:30][CH2:29][CH2:28]1.[Li+].[Cl-].N1C=C[CH:38]=[CH:37][CH:36]=1>>[CH:8]1([NH:7][C:5](=[O:6])[C:4]2[CH:13]=[C:14]([NH:16][C:23]([CH:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)=[O:24])[CH:15]=[C:2]([NH:1][C:31]([CH:30]3[CH2:38][CH2:37][CH2:36][CH2:28][CH2:29]3)=[O:32])[CH:3]=2)[CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

6

Reactant 5

HCID 1049PyridineHCID 13387N-methyl-2-pyrrolidoneHCID 75938Cyclohexanecarbonyl chlorideHCID 433294Lithium ChlorideHCID 61090893HCID 61090893, compound

Product 1

HCID 58903272HCID 58903272, compound

Procedure

from 0.62 g (2.83 mmol) of 3,5-diamino-N-cyclopentylbenzamide, 0.97 g (6.62 mmol) of cyclohexanecarbonylchloride, 30 ml of NMP, 5 ml of pyridine and 0.05 g of LiCl according to Method A

Sources & evidence

ORD record
ord-4ea9b2bb65a34166a6bd523709170f62
Source dataset
uspto-grants-2010_09
Patent number
US07790793B2

Reaction notes

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