Hydrochloric Acid → HCID 68504038, compound

HRID 1712023Notes

Reaction equation

HRID 1712023 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][CH2:11][C:10]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21]C3CCCCO3)[CH:16]=2)([OH:14])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl>C(O)C>[CH2:1]([N:8]1[CH2:13][CH2:12][CH2:11][C:10]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([OH:21])[CH:16]=2)([OH:14])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 68507203HCID 68507203, compound

Product 1

HCID 68504038HCID 68504038, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8.64 g of 1-benzyl-3-[3-(tetrahydropyrane-2-yloxy)-phenyl]-piperidine-3-ol were dissolved in 30 ml of ethanol and 8.9 ml of HCl were added. The solvent was removed after stirring the mixture for 60 hours. Yield 6 g

Workup

  1. customThe solvent was removed

Sources & evidence

ORD record
ord-7d0b454076424d5096953231acc95088
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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