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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1712035Generated: November 4, 2026

2-Thiophenecarbonyl chloride → [3-Hydroxy-3-(3-methoxyphenyl)-piperidine-1-yl]-thiophen-2-yl-methanone

https://huagongshe.com/reaction/1712035

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarbonyl chlorideHCID 78928—
Reactant3-(3-Methoxy-phenyl)-piperidine-3-olHCID 11651676—
Product[3-Hydroxy-3-(3-methoxyphenyl)-piperidine-1-yl]-thiophen-2-yl-methanoneHCID 11536987—

Reaction Steps

The compound of Example 14 was prepared according to the general preparation protocol A from thiophene-2-carbonyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790898B2
Source datasetuspto-grants-2010_09
ORD IDord-622c623594e4484d991492aefea8144f
Source noteuspto-grants-2010_09