2,2-Diphenylacetyl chloride → HCID 11632745, compound

HRID 1712049Notes

Reaction equation

HRID 1712049 reaction equation
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([C:25]2([OH:31])[CH2:30][CH2:29][CH2:28][NH:27][CH2:26]2)[CH:22]=[CH:23][CH:24]=1>>[OH:31][C:25]1([C:21]2[CH:22]=[CH:23][CH:24]=[C:19]([O:18][CH3:17])[CH:20]=2)[CH2:30][CH2:29][CH2:28][N:27]([C:8](=[O:9])[CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:26]1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11632745HCID 11632745, compound

Procedure

The compound of Example 29 was prepared according to the general preparation protocol A from diphenylacetyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-80f049ee20624f40a1b779f3fdf6e509
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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