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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1712261생성일: 2026년 10월 25일

1-Chloro-3-methoxypropane → Benzyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[1-(3-methoxypropyl)-1H-indol-4-ylmethoxy]piperidine-1-carboxylate

https://huagongshe.com/reaction/1712261

반응식

참여 물질

역할이름HCID투입량
반응물1-Chloro-3-methoxypropaneHCID 118927—
반응물benzyl 3-(1H-indol-4-ylmethoxy)-4-{4-[3-(2-methoxy-benzyloxy)propoxy]phenyl}piperidine-1-carboxylateHCID 68499385—
생성물Benzyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[1-(3-methoxypropyl)-1H-indol-4-ylmethoxy]piperidine-1-carboxylateHCID 68502492—

반응 단계

Analogously to Example 10a, 0.148 g of benzyl 3-(1H-indol-4-ylmethoxy)-4-{4-[3-(2-methoxy-benzyloxy)propoxy]phenyl}piperidine-1-carboxylate (Example 10b2) and 0.110 ml of 1-chloro-3-methoxypropane are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.25 (1:1 EtOAc-heptane); Rt=27.24 min (II).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07790715B2
출처 데이터셋uspto-grants-2010_09
ORD IDord-8a5fdfa04af24477a48844a42f8cb888
출처 메모uspto-grants-2010_09