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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1713018Generated: November 2, 2026

HCID 86618328, compound → HCID 12527106, compound

https://huagongshe.com/reaction/1713018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86618328HCID 86618328—
SolventP-XyleneHCID 7809—
ProductHCID 12527106HCID 1252710678.4%

Reaction Conditions

Temperature140 °C

Reaction Steps

The obtained 2-Azido-3-[5-(4-chloro-phenyl)-furan-2-yl]-acrylic acid ethyl ester (21 mg, 0.066 mmol) was dissolved in p-xylene and the mixture was heated to 140° C. for half an hour. The solvent was thereafter evaporated to give 15 mg (78% yield) of 2-(4-chloro-phenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester as a red solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795255B2
Source datasetuspto-grants-2010_09
ORD IDord-972ab5d505ed4d17b6d249215dc8e4ba
Source noteuspto-grants-2010_09