HCID 86618335, compound → HCID 86618334, compound

HRID 1713032Notes

Reaction equation

HRID 1713032 reaction equation
C([O:3][C:4](=[O:33])[CH:5]([CH2:31][CH3:32])[CH2:6][CH2:7][N:8]1[C:28](=[S:29])[N:11]2[C:12]3[CH:13]=[C:14]([C:18]4[CH:23]=[CH:22][CH:21]=[C:20]([C:24]([F:27])([F:26])[F:25])[CH:19]=4)[O:15][C:16]=3[CH:17]=[C:10]2[C:9]1=[O:30])C>FC(F)(F)C(O)=O.O>[CH2:31]([CH:5]([CH2:6][CH2:7][N:8]1[C:28](=[S:29])[N:11]2[C:12]3[CH:13]=[C:14]([C:18]4[CH:23]=[CH:22][CH:21]=[C:20]([C:24]([F:27])([F:26])[F:25])[CH:19]=4)[O:15][C:16]=3[CH:17]=[C:10]2[C:9]1=[O:30])[C:4]([OH:33])=[O:3])[CH3:32]

Participants

4

Reactant 1

HCID 86618335HCID 86618335, compound

Product 1

HCID 86618334HCID 86618334, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6422Trifluoroacetic acidSolvent

Conditions

Temperature
70 °C

Procedure

Compound 25 (100 mg, 0.22 mmol, prepared as described hereinabove) was dissolved in a mixture of trifluoroacetic acid and water (4:1; 3 ml) and the solution was heated to 70° C. for 7 hours.

Sources & evidence

ORD record
ord-7ab6f58022ce4048a6094d244f027f2b
Source dataset
uspto-grants-2010_09
Patent number
US07795255B2

Reaction notes

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