HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → {2-[(cyclobutylamino)carbonyl]-7,8-dihydro-1,6-naphthyridin-6(5H)-yl}acetic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59463645 | HCID 59463645 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | {2-[(cyclobutylamino)carbonyl]-7,8-dihydro-1,6-naphthyridin-6(5H)-yl}acetic acid hydrochloride | HCID 66877729 | — |
Reaction Steps
The oil obtained from step 2 is dissolved in dioxane (5 mL). 4 N HCl in dioxane (5 ml, 20 mmol) is added. The mixture is stirred at rt overnight. The solvent is removed and the residue is washed with ether to give the title compound as a white solid. MS (M+1): 290.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795262B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-0e513dc03aeb4f0eaee41fd6d4289dc1 |
| Source note | uspto-grants-2010_09 |